Browsing by Author "Bebora, L."
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Item Effects of Long Acting Oxytetracycline on Contagious Bovine Pleuropneumonia Experimentally Infected Cattle(Tanzania Journal of Science, 2022-12) Otina, B.; Kitala, P.; Bebora, L.; Olum, M.; Kipronoh, A.; Chesang, L.; Stuke, K.; Wesonga, H.; University of Nairobi ; KALRO-Veterinary Science Research Institute ; GALVmed (Global Alliance for Livestock Veterinary Medicines)Contagious bovine pleuropneumonia is an important disease of cattle. Many strategies employed for its eradication and control have had shortcomings. This study was conducted to determine the effects of long acting Oxytetracycline on its course. The study involved 30 indigenous zebu cattle sourced from an area free of the disease, infected by contact transmission and randomly allocated to Oxytetracycline or saline treatment groups. Clinical observations were recorded on the two groups concurrently. Cattle were tested for the disease using complement fixation test. The mean clinical scores of the groups for each observation was compared post treatment on GENSTAT using unpaired t-test for single sample in groups. Full post-mortem was conducted on the cattle and samples collected for Mmm SC isolation. The clinical scores were worse in the control treatment group; there was no fever in the Oxytetracycline-treated group post treatment. Lesions were observed in 93% of the control and 27% of the Oxytetracycline-treated group. In this study, as in others, Oxytetracycline was shown to lower the severity of the clinical signs of the disease. This is important at slaughter houses meat inspection where decision on whether to pass or condemn the animal is based on the clinical signs and post-mortem findings.Item Seroprevalence of Peste des Petits Ruminants and Contagious Caprine Pleuropneumonia Coinfections in Goats in Kwale County, Kenya(Hindawi, 2023-07-14) Lugonzo, G.; Gitao, G.; Bebora, L.; Lutta, H.O.; Kenya Agricultural and Livestock Research Organization ; University of NairobiGoats are among the most important small ruminants afected by Peste des Petits ruminants (PPR) and contagious caprine pleuropneumonia (CCPP) diseases, two of the most signifcant constraints worldwide to the production of small ruminant species. Herein, the competitive enzyme-linked immunosorbent assay (cELISA) and the latex agglutination test (LAT) were used to determine the coinfections of PPR and CCPP in goats in Kwale County on Kenya’s South Coast. A total of 368 serum samples were collected from goats of various ages and sexes exhibiting respiratory distress in the four subcounties of Kwale County (Kinango, Lunga Lunga, Matuga, and Msambweni) and screened for PPR and CCPP antibodies. Of the 368 goats sampled, 259 (70.4%) were females and 109 (29.6%) were males, and 126 (34.2%), 71 (19.3%), 108 (29.3%), and 63 (17.1%) samples were collected from Kinango, Matuga, Lunga Lunga, and Msambweni, respectively. Te overall PPR seropositivity rate was 48.6% (179/368); rates in Kinango, Lunga Lunga, Matuga, and Msambweni were 70.6%, 29.6%, 49.3%, and 36.5%, respectively. Te overall CCPP se-ropositivity rate was 45.4% (167/368), while rates in Kinango, Lunga Lunga, Matuga, and Msambweni were 51.6%, 49.1%, 36.6%, and 36.5%, respectively. Notably, the seropositivity of PPR was higher in male (53.3%) than in female (46.72%) goats, though not statistically signifcant. In addition, the CCPP seropositivity rates were not signifcantly diferent between male (44.0%) and female (45.9%) goats. Regarding age, the PPR seropositivity rates were 45.9%, 55.8%, and 52.3% in adults, kids, and weaners, respectively. For CCPP, the seropositivity rates were 48.3%, 40.4%, and 42.3% in adults, kids, and weaners, respectively. Te coinfection rate of PPR and CCPP was 22.3% (82/368). Despite the high coinfection, univariate analysis revealed no relationship between PPR and CCPP infections. However, given the high PPR and CCPP infection rates, as a result of separate or coinfection, there is a need to upscale or intensify vaccination in the county.
