Browsing by Author "Dolan, T. T."
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Item Immunization againist Theileriosis on OL Pejeta Ranch,Laikipia,Kenya(Kenya Trypanosomiasis Research Institute, 1983) Dolan, T. T.; Kenya Trypanosomiasis Research Institute; Veterinary Research Department KARI Muguga01 Pejeta is a large Ranch in the Laikipia District of Kenya. It is situated on the equator at 6000 ft., :and has an annual rainfall of 27 inches. It grazes about 12,000 head of cattle and 6000 sheep together with large herds of elephant, zebra, antelope, giraffe and buffalo. Tick bOJ1ne diseases are the major veterinary problem on the ranch, of which East Coast fever/Corridor disease is the most important. Tick control is maintained by dipping or spraying in acaricide once, twice or three times each week, depending upon rainfall or disease challenge.Item Synchronization of the division of Theileria macroschizonts and their mammalian host cells(Annals of Tropical Medicine and Parasitology, 1980) Stagg, D. A.; Chasey, D.; Morzaria, S. P.; Dolan, T. T. ; Veterinary Research Department, Kenya Agricultural Research Institute, Muguga; Veterinary Research Department, Kenya Agricultural Research Institute, Muguga; Central Veterinary Laboratory, New Haw, Weybridge, Surrey, U.K.Theileria macroschizonts transform the parasitized lymphoid cells of their mammalian host’s in vivo and ill litro so that the cells become lymphoblastoid, there is a massive proliferation of infected cells and new antigens arc expressed on the cell surface (Brown et at., 1973; De: Martini and Moulton, 1973; Pearson et al., 1979). During the division of the host cells in litro the macroschizonts normally abo divide so that two infected daughter cells are produced (Hulligcr et al., 1964). The end product of macroschizont division in Vivo, and ccasionally ill 1'ltro, is the microschizont and the resultant merozoites are released with the destruction of the host cell.
