Browsing by Author "East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya, Africa"

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The Development of Forssman Antibody in the Sera of Cattle Following Vaccination and Infection with Contagious Bovine Pleuropneumonia
(1974) Kakoma, I.; Stone, S.S.; East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya, Africa
Cattle are Forssman antigen (Fog) free and naturally have a very low level of Forssman antibody (Fob). After exposure to, or vaccination with, Mycoplasma mycoides var, mycoides which contains Fog, Fob develops in the sera of these cattle. The Fob appears before the complement fixing antibody and in vaccinated cattle persists longer. The Fob is primarily a macroglobulin as indicated by 2-mercaptoethanol sensitivity. The sero-diagnostic importance of the Fog-Fob system is discussed.