Browsing by Author "Jarrett, W.F.H."
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Item Experiments in Immunity to East Coast Fever(1965) Brocklesby, D.W.; Bailey, K.P.; Jarrett, W.F.H.; Martin, W.B.; Miller, H.R.P.; Nderito, P.; Urquhart, G.M.; University of East Africa, P.O. Kabete, KenyaSpleen suspension from cattle in the late hyper-plastic stage of Theileria parva infection, injected i/v in doses of 0.1-5 ml., protected 15 of 19 cattle from tick-induced infectionItem A Preliminary Electron Microscopic Study of East Coast Fever (Theileria Parva Infection)(1966) Jarrett, W.F.H.; Brocklesby, D.W; East African Veterinary Research Organization, Mugaga, P.O. Box 32, Kikuyu, KenyaThe fine structure of various stages in the life cycle of Theileria parva is described. The appearance of the parasites suggests that there may be a double macroschizogony cycle. Micromerozoites are produced by a process of budding off from the body, known in light microscopy preparations as the residual body.Item The Transmission of East Coast Fever Using Cells from Infected Animals(1964) Jarrett, W.F.H.; Jennings, S.; Martin, W.B.; Urquhart, G.M.; Nderito, P.; Brocklesby, D.W.; Bailey, K.P.; University of Glasgow Veterinary Hospital, Glasgow (U.K.); Veterinary Faculty, University of East Africa; E.A.V.R.O. Muguga (Kenya)This chapter describes the transmission of east coast fever using cells from infected animals. Four experiments using 26 cattle were carried out. In the first, a suspension of spleen and lymph node cells was prepared from a field case which was in the late hyperplastic stage of the disease. It was implanted interperitoneally into two animals, both of which showed a typical severe clinical and pathological reaction. They were killed in the late hyperplastic stage and cell suspensions prepared from their spleens. Two further passages were then carried out using a similar technique but smaller volumes of cells. It is found that of the 16 animals infected, 7 died, or were killed in extremis, 6 reacted severely and recovered, while 3 showed a clinical reaction but did not have demonstrable parasites. In the second experiment, cells from a field case were implanted by the interperitoneal route into an animal, and when this was in extremis it was killed and a cell suspension was prepared. The intravenous route was then used successfully to infect two other cattle.
