Browsing by Author "Muthomi, E."
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Item The Effect of Some Climatic Factors on the Incidence of Caprine Pleuropneumonia in the Sultanate of Oman(1992) Litamoi, J.K.; King, G.J.; Njuho, P.M.; Muriu, D.; Kagumba, M.; Muthomi, E.; Kenya Agricultural Research Institute, National Veterinary Research Centre, Muguga, Kenya.Contagious caprine pleuropneumonia (CCPP) is an economically important mycoplasmal disease of goats with a wide geographical distribution. Apart from inducing cold stress, low temperatures may extend the life of disease-causing organisms, increase the tendency of animals to huddle together, thereby decreasing ventilation. These factors in combination can favour an increased level of airborne microbials, thus increasing the chances of disease outbreak. Dry weather on the other hand, which tends to be associated with more light, reduces the risk of spread of disease because of rapid evaporation and more ultraviolet radiation which can lead to the inactivation of disease agents such as mycoplasmas.Item Short Communications(1981) Rurangirwa, F.R.; Masiga, W.N.; Muthomi, E.The F-38 strain of mycoplasma causes acute contagious caprine pleuropneumonia in goats in Kenya (MacOwan and Minette 1976), It has been shown to cause a disease with 100 per cent morbidity and mortality in susceptible goats under laboratory conditions (Rurangirwa and others 1981), However. when affected goats are treated with streptomycin on the third day of temperature reaction (40°C or higher), they recover from the disease and become completely immune to reinfection with F-38 (Rurangirwa and others 1981), Serum samples from such recovered goats have growth inhibiting activity against F-38 (unpublished observation), Reported below is a trial to determine whether induction of growth inhibiting antibodies in goats using inactivated F-38 antigens would also render them immune to challenge,Item Treatment of Contagious Caprine Pleuropneumonia(1981) Muthomi, E.; Rurangirwa, F.R.; Masiga, W.N.; Muriu, D.N.; Mulira, G.; Kagumba, M; Nandokha, E.; Kenya Agricultural Research Institute; Veterinary Research DepartmentA combination of dihydrostreptomycin sulphate (250 mg/ml) and penicillin G procaine (200,000 iu/ml) was used to treat contagious caprine pleuropneumonia caused by F38 strain of mycoplasma. A single dose of either 20, 30, 40 or 50 mg/kg body weight of the dihydrostreptomycin sulphate led to the recovery of the treated goats. The recovered goats did not transmit CCPP to susceptible goats housed with them for 2 months. The goats which recovered were found to be solidly immune to an in-contact challenge in which all the control goats died of CCPP. The treated and recovered goats were found not to be carriers of the organism.
