Browsing by Author "Spooner, P.R."
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Item Characterisation of Stocks of Theileria Parva by Monoclonal Antibody Profiles(1983) Minami, T.; Spooner, P.R.; Irvin, A.D.; Ocama, J.G.R.; Dobbelaere, D.A.E.; Fujinaga, T.; International Laboratory for Research on Animal Diseases, Nairobi.Sixteen monoclonal antibodies, raised against macro-schizonts of Theileria parva, were tested against 10 different stocks of the parasite. The indirect fluorescent antibody test was used to demonstrate that these antibodies showed different binding affinities to macroschizonts of the various stocks. A profile of antibody binding could thus be prepared for each stock. For a given stock the profile was consistently the same irrespective of culture passage level, host cell background and method of antigen preparation.Item East Coast Fever the Significance of Host Ace in Infection or Immunization of Cattle with Theileria Parva(1979) Irvin, A.D.; Dobbelaere, D.A.E.; Morzaria, S.P.; Spooner, P.R.; Dolan, T.T.; Young, A.S.; Gettinby, G.; International Laboratory for Research on Animal Diseases, Nairobi, Kenya; Kenya Agricultural Research Institute, Muguga, Kenya; University of Strathclyde, Glasgow, UKT a number of tick-borne diseases of cattle, young animals show a significant resistance to infection which is independent of maternally transferred or acquired immunity. Such resistance has been detected in babesiosis (Riek 1968, Zwart and Brocklesby, 1979) an: lasmosis (Ristic, 1968; 1981) and heartwater (Uilenberg, 1983), but,10 evidence for an age-related innate resistance has been described in theileriosis apart from the rather equivocal data reported by Adler and Ellenbogen (1935) for calves infected with Theileria annulata.
