Browsing by Author "Stone, S.S."
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Item The Development of Forssman Antibody in the Sera of Cattle Following Vaccination and Infection with Contagious Bovine Pleuropneumonia(1974) Kakoma, I.; Stone, S.S.; East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya, AfricaCattle are Forssman antigen (Fog) free and naturally have a very low level of Forssman antibody (Fob). After exposure to, or vaccination with, Mycoplasma mycoides var, mycoides which contains Fog, Fob develops in the sera of these cattle. The Fob appears before the complement fixing antibody and in vaccinated cattle persists longer. The Fob is primarily a macroglobulin as indicated by 2-mercaptoethanol sensitivity. The sero-diagnostic importance of the Fog-Fob system is discussed.Item Observations on the Epizootiology of African Swine Fever(1965) Heuschele, W.P.; Stone, S.S.; Coggins, L.; East African Veterinary Research Organisation, Muguga. KenyaAn outbreak on a pig farm complying with the pig-paddocking ordinance, designed to prevent contact with the wild pig reservoir, may have been caused by farm labourers killing wild pigs for food. The role of ectoparasites needs further investigation.Item The Role of the Hippopotamus in the Epizootiology of African Swine Fever(1965) Stone, S.S.; Heuschele, W.P.; Muguga, KenyaSpleens from 317 hippopotami shot in Queen Elizabeth Park, Uganda, were tested for the presence of African swine fever (ASF) virus by the hemadsorption test and found to be negative. Similar negative results were obtained when susceptible pigs were inoculated with suspensions of spleen from 57 of these hippopotami. Negative results for ASF antibody were obtained by the complement-fixation and agar gel diffusion precipitin tests with sera from 297 of these hippopotami.Item The Validity of the Sodium Sulphite Test for Detecting Immunoglobulins in Calf Sera(1969) Stone, S.S.; Gitter, M.; East African Veterinary Research Organisation, Muguga, KenyaThe validity of the 36 per cent sodium sulphite turbidity test (SSTT) to detect the presence of globulins in young calf serum was confirmed using immunoelectrophoresis (IEP) and complement fixation tests (CFT). Immunoglobulins (Ig) could be detected in the sera of calves 2-19 hours after sucking colostrum, and these findings were correlated by I EP and CFT. The SSTT-negative sera were agammaglobulinaemic on IEP analysis. Concentrations of Na2SO3 lower than 35 per cent gave false negative results with normal calf sera, and concentrations of 40-45 per cent gave false positive results with agammaglobulinaemic calf sera. The major Ig transferred from the colostrum to the serum of the calf appears to be IgG, which is similar to that found in the colostrum.
