Browsing by Author "Vidler, B.O."
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Item Attempts to Infect Some Small Laboratory Animals with Theileria Parva(1961) Brocklesby, D.W.; Vidler, B.O. ; East African Veterinary Research Organisation, MugugaRESEARCH ON EAST COAST FEVER (T. parlla infection) has been considerably hampered by the lack of a small laboratory host animal. All investigations have to be undertaken using as experimental animals, cattle, which are both cumbersome and expensive. This fact led some investigators to seek an alternative in tissue culture (Tsur, Neitz and Pols, 1957; Brocklesby and Hawking, 1958) but none of these attempts was very successful. It is generally assumed that all small laboratory animals are insusceptible to infection with T. parva, but a search of the literature failed to reveal reports of any extensive attempts to infect such animals. Jansen (1952) splenectomized 2 dassies (Procavia capensis) 16 and 21 days after infestation with infected Rhipicephalus appendiculatus nymphae, but no development of T. parlla took place. Barnett and Bailey (1955) were not able to infect a small number of rabbits, guinea-pigs or hamsters. Barnett (1956), however, succeeded in maintaining a parasitaemia in goats by the repeated intravenous injections of infected bovine blood. Ticks which fed on one of the goats subsequently transmitted the disease to cattle. It is probable that other attempts remain unpublished.Item Further Attempts to Infect Laboratory Animals with Theileria Parva(1962) Brocklesby, D.W.; Vidler, B.O.; East African Veterinary Research Organisation, MugugaWe have continued with our attempts to infect small laboratory animals with Theileria parva (Brocklesby & Vidler, 1961). The methods that were applied to Mesocricetur auratus, Oryctolagus Uniculus, Rattus natalensis and Arvicanthis abyssinicus have now been used to attempt to infect young adults of our laboratory strain of white mice. Each group contained 5 animals.Item Haematozoa Found in Wild Members of the o Artiodactyla in East Africa(1966) Vidler, B.O. ; Brocklesby, D.W.; East African Veterinary Research OrganizationDuring the last ten years we have been interested in the haematozoa (blood protozoa) of wild animals: since our stay in Kenya is drawing to a close we feel that we should now mention the various records that have accumulated. Our main concern was to discover whether the parasites were infective for domestic animals and this has been shown to be so in several instances. Most work has been done with the African Buffalo (Syncerus caffer Sparrman) and this animal was demonstrated to be a reservoir of East Coast Fever (Theileria parva infection).Item Some Parasites of East African Wild Animals(1965) Brocklesby, D.W.; Vidler, B.O.; East African Veterinary Research Organization, Muguga, Kenya.It has been our custom during the last few years to keep a chart in our laboratory showing some of the parasites that we detect in blood smears and other preparations taken from wild animals. This "rogues' gallery" generally seems to interest visitors so we have thought it worthwhile to publish it both as a preliminary report and also to encourage the many people who kindly send us material from wild animals to continue to do so.Item Studies on Macroschizonts of Theileria parva(Elsevier, 1961) Barnett, S.F.; Brocklesby, D.W.; Vidler, B.O.; East African Veterinary Research Organisation, MugugaA series of measurements was made of the schizonts of Theileria parva in the hope that these criteria might be used in the differential diagnosis of the theilerial species. Macroschizonts were found to have an average size of 4.8 μ, which was smaller than expected. They contained from 1 to 85 nuclei, with an average of 8. In autopsy smears there were from 4 to 760 schizonts per thousand lymphocytes, with an average of 264. The degree of parasitosis at death was not correlated with the duration of illness. A plea is made for the use of the terms ‘macroschizonts’ and ‘microschizonts’ in place of the more traditional ‘agamonts’ and ‘gamonts’.