Artificial Reproduction of Contagious Bovine Pleuropneumonia

Abstract

The experimental reproduction of C.B.P.P. in cattle appears to have been resolved, the virulence of the strain used being of importance: where less virulent strains are used, some form of stress appears to be necessary for the development of acute lung lesions. Sheep and goats are susceptible to s/c inoculation but a large inoculum appears to be necessary. Laboratory animals are not susceptible unless the organisms are incorporated in an agar base. It is possible that stress would assist in the adaptation of M. mycoides to these animals. Other than cattle the chick embryo is probably the most useful experimental host. (AS).