Cell Fusion Using Sendai Virus to Effect Interspecies Transfer of Cell Associated Parasite

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1974

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Baby hamster kidney (BHK) cells were fused with Theileria parva-infecled bovine lymphoid cells, using u.v. light-inactivated Sendai virus. The resultant hamster/bovine heterokaryons were shown to be infected with T. parva. In some cases parasites were detected in cells which apparently contained only BHK nuclei.

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Irvin, A. D., Brown, C. G. D., Kanhai, G. K., Stagg, D. A., & Rowe, L. W. (1974). Cell fusion, using sendai virus, to effect inter-species transfer of a cell-associated parasite (Theileria parva). International journal for parasitology, 4(5), 519-521. https://doi.org/10.1016/0020-7519(74)90070-8

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