Theileria Annulata: Cross-Reactions between a Cell Culture Schizont Antigen and Antigens of East African Species in the Indirect Fluorescent Antibody Test

dc.bibliographicCitation.endpage380en
dc.bibliographicCitation.stpage374en
dc.bibliographicCitation.titleEast African Agricultural And Forestry Journalen
dc.bibliographicCitation.volume35en
dc.contributor.authorBurridge, M.J.
dc.contributor.authorBrown, C.G.D.
dc.contributor.authorKimber, C.D.
dc.contributor.institutionEast African Veterinary Research Organization, Muguga, P. O. Box 32, Kikuyu, Kenya
dc.date.accessioned2015-07-16T09:35:05Z
dc.date.available2015-07-16T09:35:05Z
dc.date.issued1974en
dc.description.abstractA schizont antigen for the indirect fluorescent antibody test was prepared from an in vitro culture suspension of lymphoid cells infected with Theileria annulata macroschizonts. Two cattle recovered from T. annulata infection showed marked rises in antibody titer to this schizont antigen, with peak titers of 1:40,960 and 1:2560. Using sera from these recovered cattle, T. annulata cell culture schizont antigen was shown to cross-react markedly with Theileria parva and Theileria lawrencei cell culture schizonts and with Theileria mutans piroplasms in the indirect fluorescent antibody test. In contrast, using high-titer antisera to T. parva, T. lawrencei, and T. mutans, serological cross-reactions with T. annulata schizonts were only detected with T. parva and T. lawrencei antisera, and in both instances these were minimal. The value of the indirect fluorescent antibody test in the differential diagnosis of Theileria species pathogenic for cattle is discussed.en
dc.description.notesImmunological Research on Tick-borne Cattle Diseases and Tick Control Project, East African Veterinary Research Organization, Muguga, P. O. Box 32, Kikuyu, Kenyaen
dc.identifier.citationBurridge, M.J., Brown, C.G.D., & Kimber, C.D. (1974). Theileria annulata: Cross-reactions between a cell culture schizont antigen and antigens of East African species in the indirect fluorescent antibody test. Experimental Parasitology, 35(3), 374–380. https://doi.org/10.1016/0014-4894(74)90043-5 en
dc.identifier.doihttps://doi.org/10.1016/0014-4894(74)90043-5
dc.identifier.issn0012-8325*
dc.identifier.urihttps://kalroerepository.kalro.org/handle/0/4817
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/en
dc.subject.agrovocTheileria annulataen
dc.subject.agrovocCell cultureen
dc.subject.agrovocAntigensen
dc.subject.agrovocFluorescent antibody techniqueen
dc.titleTheileria Annulata: Cross-Reactions between a Cell Culture Schizont Antigen and Antigens of East African Species in the Indirect Fluorescent Antibody Testen
dc.typeJournal Contribution*
dc.type.refereedRefereeden
dc.type.specifiedArticleen

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