The Production of Caprinised Rinderpest Vaccine

Abstract

The Kabete attenuated goat (K.A.G.) strain of caprinised rinderpest virus has proved to be the most successful agent in the control• of rinderpest in Africa. Daubney (1949) estimated that at least fifteen million cattle had been immunized with K.A.G. by 1948 and since then a further forty million cattle have been vaccinated. Despite the widespread use of K.A.G., details of this production technique have hitherto not been published. Our current methods are an elaboration of Daubney and Hudson's original technique for the production of dried infected goat spleens at the Veterinary Laboratory, Kabete, and owe much to Brotherston's, Burdin's, and Scott's later innovations.