Njiru, Z.K.Mukani, W.O.Khaemba, B. M.Ochieng, R.S.Ndungu, J.M.2015-08-192015-08-192000Njiru, Z. K., Olaho-Mukani, W., Khaemba, B. M., Ochieng, R. S., & Ndung'u, J. M. (2000). Haematological and Serological Changes During acute Trypanosoma evansi Infection in Dromedary camels (Camelus dromedarius). Journal of Camel Practice and Research, 2000, Vol. 7, ( 1), 113-116 . https://www.cabidigitallibrary.org/doi/full/10.5555/2000222108509716777https://kalroerepository.kalro.org/handle/0/10194The pathological effects of acute T. evansi infection in camels, haematological and serological parameters were assessed in 5 experimentally infected camels. The role of these parameters in immunosuppression and sudden death in sick camels was also investigated. Following infection, there was a massive leukocytosis characterised by lymphocytosis, neutrophilia and a mild eosinophilia. Monocyte, basophil and packed cell volume changes were negligible. There was a significant reduction (p<0.05) in haemolytic complement and an increase in complement fixing antibodies. These parameters returned to pre-infection levels after i.m. treatment with melarsomyl (Cymerlsan) at 0.25 mg/kg body weight. These results indicate that the activation of haemolytic complement during acute infection may be a major factor contributing to death in camels infected with trypanosomosis.enhttp://creativecommons.org/licenses/by/3.0/Journal ContributionSerologyTrypanosoma evansiInfectionCamelsDromedarieshttps://www.cabidigitallibrary.org/doi/full/10.5555/20002221085