Passive Transfer of Immunity and Formation of Lung Lesions in Cattle following Intravenous Inoculation of Antibody and Mycoplasma

Abstract

Intravenous inoculation of hyperimmune or immune bovine serum into cattle 24 hours before intravenous inoculation of the virulent Gladysdale strain of M. mycoides transferred passive immunity as judged by the absence of oedematous reaction of Willems at the mycoplasma inoculation site. Lung lesions of CBPP developed in two cattle that had received hyperimmune or immune serum before the intravenous inoculation of mycoplasma, but also a small lesion developed in one animal not previously inoculated with serum.