Hybrid Cells, Infected with Theileria Parva, Formed by Fusion of Hamster and Mouse Cells with Parasitised Bovine Lymphoid Cells
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Date
1975
Authors
Irvin, A.D.
Brown, C.O.D.
Stagg, D.A.
Kanhai, O.K.
Rowe, L.W.
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Abstract
Bovine lymphoid cells from a culture line parasitised with Theileria parva were fused to mouse heart (MH) and baby hamster kidney (BHK) cells, grown as monolayers, using inactivated Sendai virus. The resultant heterokaryons contained macro schizonts of T parva. Macro schizonts also occurred in cells that apparently contained only BHK or MH nuclei. Parasites underwent varying degrees of development; in some cases, micro schizonts resulted, and in other cases massive atypical parasite masses were formed. Fusion occurred more readily between hamster and bovine cells than between mouse and bovine cells.
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Citation
Irvin, A.D., Brown, C.G.D., Stagg, D.A., Kanhai, G.K., & Rowe, L.W. (1975). Hybrid Cells, Infected with Theileria Parva, Formed by Fusion of Hamster and Mouse Cells with Parasitised Bovine Lymphoid Cells. Research in veterinary science, 19(2), 142-151. https://doi.org/10.1016/S0034-5288(18)33524-0
